CAS:112827-99-3|(24R)-Calcipotriene

2025-08-08 1 0

产品名称:(24R)-Calcipotriene
同义名称:5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4R)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol; (1α,3β,5Z,7E,22E,24R)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol; PRI 2202; Calcipotriol, anhydrous specified impurity D [EP]; Calcipotriol EP Impurity D
Impurity:Calcipotriol EP Impurity D
CAS 号:112827-99-3
分子式:C₂₇H₄₀O₃
性状:White to Off-White Solid
熔点:144-147°C
分子量:412.6
存储:-20°C
溶解度:Chloroform (Slightly), Methanol (Slightly)
Stability
Light sensitive, Temperature sensitive
产品类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:(24R)-Calcipotriene (Calcipotriol EP Impurity D) is a synthetic analogs of vitamin D that was studied for its potential antitumor effects. Studies has shown the combined treatment with vitamin D analog (24R)-Calcipotriene was more effective than the treatment with cytostatics applied alone. (24R)-Calcipotriene is also the 24-R epimer of Calcipotriene (C144200).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献:Wietrzyk, J., et al.: Anticancer. Res., 27, 3387 (2007); Tien, X.Y., et al.: Am. J. Physiol., 265, 143 (1993); Wietrzyk, J., et al.: Anti-Cancer. Drugs., 18, 447 (2007);
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